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Similar content being viewed by others Introduction Allergy to antibiotics is a major health problem in Europe, with betalactams (BLs) the most frequent culprits 1,2

125 YamamotoA.ShinR

10.1111/jcmm.16852 119

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Here, we propose a reinforced mode of the gutbone axis plus X that the gutbone axis synergizes with other tissues or organs in the form of additive effects on clinical manifestations and mechanisms of action that are in tandem, constructing a broader biological network at the core of the gutbone axis while spreading to other systems of the organism