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Accumulation of Succinyl Coenzyme A Perturbs the Methicillin-Resistant Staphylococcus aureus (MRSA) Succinylome and Is Associated with Increased Susceptibility to Beta-Lactam Antibiotics

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A milder nonclassical form of P450scc deficiency caused by missense mutations that retain 10-20% of normal activity has been described recently (323, 324)