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This is a judgment call that depends on specific circumstances and how questions are phrased

The literature sources used in this review were PubMed, Google Scholar, Scopus, and Web of Science databases

doi: 10.1038/s41419-020-2298-2

357 The in vitro culture of telomere-binding protein protection of telomeres 1 (Pot1) in HSCs has been demonstrated to maintain self-renewal capacity and regulate the activity of HSCs in elderly individuals, which has significant implications for the ex vivo cultivation of human HSCs

Bioregulator peptides like Pinealon and Cortagen, while small and relatively stable, still require proper cold chain management