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Using co-immunoprecipitation (CO-IP), the study confirmed that FOXO4-DRI prevents FOXO4 binding to p53, facilitating phosphorylated p53 nuclear exclusion, which triggers BAX upregulation and cleaved caspase-3 activation driving selective apoptosis of senescent endothelial cells

doi: 10.1016/s0278-6915(99)00087-3

The anti-inflammatory effects of selenium are mediated through 15-deoxy-12,14-prostaglandin J2 in macrophages

Seropositive AIH is usually classified based on the autoantibody profile: type 1 AIH is labeled in the presence of ANA or ASMA antibodies, while type 2 AIH is diagnosed in the presence of LKM-1 or anti-LC-1 antibodies [9, 42, 50, 53]

Yuksel et al, 2015) and follicle atresia leading to premature activation of the finite primordial follicle pool, leading to premature depletion of the ovarian reserve (Goldman et al, 2017