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At the same time, immune system chemicals (cytokines) call in immune cells that attack the nerves, causing more injury

Interested parties' input was gathered at two Provider Leadership Workgroup meetings, two Person and Family Engagement Workgroup meetings and one Technical Expert Panel meeting between 2023 and 2024 in addition to the public comment period correlated with the Safety of Care Request for Information included in the CY 2025 OPPS Proposed Rule (89 FR 94514 through 94521)

In a 16-week trial, newly diagnosed ALS patients taking 50 mg of methylcobalamin experienced a 43% reduction in disease progression, though further research is needed