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None of the combination-specific risks have been characterized in a human trial because that trial does not exist

Research protocols typically use daily dosing for 714 days during the induction phase, with therapeutic effects lasting 30+ days post-treatment despite complete plasma clearance within 12 hours of the final dose

Although they are not typically considered part of the BBB, microglia survey the CNS for microbes and have the capabilities to engulf and destroy those they encounter

Sikiri et al., Bone, 1999, 24, 195202)

Cell proliferation assay To assess the influence of BPC-157 on cell growth, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cell proliferation assay was used