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their mean age was around nine years old, and all of them were on HU stable dose at enrollment, as long-term use of HU is safe and well-tolerated in large cohorts of children and adults with SCD, reducing mortality and morbidity of both children and adult patients [30, 31]

MTAP deficiency prevents tumors from recycling the polyamine metabolism byproduct methylthioadenosine (MTA) back into Met, forcing reliance on exogenous Met, while simultaneously increasing sensitivity to purine synthesis inhibitors (68)

Milk kefir has gained recognition among various functional foods for its potential diabetic control properties (Salari et al., 2021

Higuchi, "Ubiquinol-10 Supplementation Activates Mitochondria Functions to Decelerate Senescence in Senescence-Accelerated Mice", Antioxid

& Coussens, L