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As previously mentioned, iron plays a role in APAP-caused hepatotoxicity

Eur J Endocrinol 2019

Glucocorticoids and insulin: reciprocal signals for energy balance

It also assists in detoxification processes within the body

In contrast, the model group received up to three intraperitoneal injections of freshly prepared STZ (45 mg/kg/day) in sodium citrate buffer, administered every other day