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Among individuals with CSF and plasma data, AD cases corresponded to those with a diagnosis of dementia of the Alzheimers type (DAT) using criteria equivalent to the National Institute of Neurological and Communication Disorders and Stroke-Alzheimers Disease and Related Disorders Association for probable AD 58 , and AD severity was determined using the Clinical Dementia Rating (CDR) 59 at the time of lumbar puncture (for CSF samples) or blood draw (for plasma samples)

Plant Cell 27:25452559 Chen C, Chen H, Zhang Y, Thomas HR, Frank MH, He Y, Xia R (2020) TBtools: an integrative toolkit developed for interactive analyses of big biological data

[Google Scholar] 54.Mic O.M., Mic L.C., Huzum B., Neamu A.A., Cerbu S., Chioiba D.R., Criniceanu P.Z., Motoc A.G.M

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By combining appetite suppression with increased energy expenditure and enhanced fat oxidation, mazdutide offers significant advantages over traditional GLP-1only therapies