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Hence, it is also possible to assess the occurrence of an in vivo DILI episode by monitoring liver biomarkers in other biological fluids such as serum or urine, obtained by non-invasive or minimally invasive procedures, avoiding the need for liver biopsies for diagnostic purposes

For the DPPH assay, a 0.1 mM DPPH solution was prepared in methanol

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Gain-of-function mutations disrupt this equilibrium by enhancing cation leakage and facilitating the dehydration of RBCs, resulting in hereditary xerocytosis

Unlike most dietary antioxidants that are distributed broadly throughout the body, ergothioneine is actively concentrated in cells and tissues that experience the highest levels of oxidative stress: red blood cells, the liver, kidneys, eyes, bone marrow, and seminal fluid