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Nucleic Acids Res 41:68166827

doi: 10.3390/biomedicines8020037 Gonzales, Junior, Pirovano, Giacomo, Chow, Chun Yuen, de Souza Franca, Paula Demetrio, Carter, Lukas M., Klint, Julie K., Guru, Navjot, Lewis, Jason S., King, Glenn F

913 Phase III involves metabolite transport in the form of biliary excretion that requires transporters

GI dysfunction, a common comorbidity in PD, further contributes to fluctuations in levodopa absorption and plasma concentrations, thereby triggering or exacerbating the on-off phenomenon [86, 87]