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After a 7-days acclimatization period, the mice were randomly assigned to five groups ( n = 8 per group), Normal Control (NC) group: did not undergo modeling induction

10.1016/j.tips.2020.11.009 95 MaY.ThurechtK

DFO, while effective in animal models, exhibits poor bloodbrain barrier (BBB) permeability, necessitating intranasal or intracerebroventricular delivery to achieve therapeutic concentrations (Guo et al., 2013)