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( d ) Normalized BRET responses to the maximum amplitude induced by ghrelin are shown

doi: 10.1016/j.cobme.2022.100390

UV PROTECTION Helps shield the skin from daily UV exposure, minimizing sun-related damage and preventing uneven tone

A simple melasma skincare routine is as follows: AM: Ascorbic acid- vitamin C, SPF, polypodium 480 mg, vitamin C tablet orally Midday: Sunscreen reapplication, lotion, stick or spray, polypodium 480 mg PM: 20% Azelaic acid, melatonin 3-5 mg taken nightly, option for glutathione tablets The combination of choice will be determined by our dermatologist at The Melasma Clinic

During a median follow-up of 15.9 months (range: 12.0-29.7 months), six patients experienced ischaemic recurrences (four patients had one recurrence, one patient had two, and one had three), which represents and incidence rate of 0.04 per person/year