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mtDNA showed much higher levels of oxidized bases than nDNA, in agreement with the fact that mitochondria are the major site for free radical production, thereby showing higher levels of oxidative stress

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The fluorescence of R6G labeled nanocarriers in the cell lysates were measured by spectrofluorometer (Fluorolog 3, Horiba Jobin Yvon, USA) at 525 nm excitation and 551 nm emission wavelengths

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