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They: Produce collagen Organize extracellular matrix Restore tensile structure In experimental tendon transection models, BPC-157 has been associated with: Increased fibroblast density Enhanced migration into injury site Accelerated granulation tissue formation Proposed signalling involvement includes: FAK (Focal Adhesion Kinase) activation ERK1/2 signalling Src pathway modulation FAK signalling is particularly important because it regulates: Cell adhesion Cytoskeletal reorganization Migration along collagen scaffolds Tendon strength depends not just on collagen quantity but alignment

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Mayr B, Schaffner G, Kurzbauer R, Schneider A, Reifinger M, Loupal G (1995): Mutations in tumour suppressor gene p53 in two feline fibrosarcomas

Lanphear B, Navas-Acien A, Bellinger DC

Category 2: Saccharomyces boulardii Category 3: Soil-Based Blends, usually Bacillus species Using one type is good, but using all three together is often best for maximum benefit