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By the late 1970s, a consensus emerged about the importance of studying autism independently of schizophrenia, which promoted the updating of diagnostic criteria

Finally, establish realistic timelines for metabolic improvements, recognizing that benefits typically emerge gradually over several months of treatment

Systemic/non-ophthalmic exclusion criteria General history judged by the investigator to be incompatible with the study (for example, life-threatening patient condition or other condition where post-operative follow-up may be difficult)

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