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Peptides like this one are fragile molecules, and an injectable, subcutaneous form is generally the most predictable way to deliver a known, stable amount into the body

AOD 9604 is a synthetic peptide fragment derived from the C-terminus of human growth hormone (hGH), specifically amino acids 176191

While clinical development for obesity was discontinued in 2007 after a Phase IIb trial failed to achieve its primary endpoint, the peptide remains a valuable research tool for investigating adipose tissue biology, lipolytic pathways, and receptor-independent signaling mechanisms

For diagnostic purposes, PET and SPECT tracers require radionuclide labels, emitting positrons and gamma rays respectively, with half-lives matching the biological half-life of the targeting vector

Furthermore, evidence for changes in the level of blood or tissue mitochondrial function or metabolic readouts is currently lacking for these studies