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Ischemic heart disease including myocardial infarction and chronic ischemia could potentially benefit from the peptide's cardioprotective effects, enhanced coronary angiogenesis, and anti-arrhythmic properties demonstrated in animal models

J Comp Neurol 350:412438 Mansour A, Fox CA, Akil H, Watson SJ (1995) Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications