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Remarkably, beneficial effects have been observed across this 100-fold range, suggesting a wide therapeutic window where smaller doses remain biologically active

The addenda relating to the OPPS are available at

I had injection site pain, headache and body aches for 48 hours

[PubMed] [Google Scholar] Gjurasin M, Miklic P, Zupancic B, et al

2006 Severe vitamin B12 deficiency in an exclusively breastfed 5-month-old Italian infant born to a mother receiving multivitamin supplementation during pregnancy.[BMC Pediatr