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[9] The Long R3 design pushes the same principle further: the Arg-for-Glu swap at position 3 removes a residue important for binding-protein contact, and the 13-residue N-terminal extension further perturbs the IGFBP interface

two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function

As articular cartilage is an important structural and functional unit of the joint, cartilage degeneration and damage can cause impairment and loss of joint function in RA patients (94)

Ed.) 2010;63:10961099