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Pharmacological treatments are the most widely available and have the greatest variety of options and a number of novel pharmacological treatments are presented as highlights, including JAK enzyme inhibitors

175,176 STATs are phosphorylated and translocated into the nuclear compartment to transcriptionally upregulate specific genes, 177 often leading to cell proliferation or differentiation

Dana Foundation

Several clinical trials have focused on encapsulating and delivering chemotherapeutics in nanoparticles for the treatment of brain tumors and metastases (9)