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Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimers disease and Parkinsons disease: a large-scale multi-trait association analysis

2017;26:55867.e5

For instance, LXR, a nuclear receptor for oxysterols, represses the expression of CYP51A1 and farnesyl-diphosphate farnesyltransferase 1 (FDFT1) in human HepG2 and HEK293 cells by binding to negative LXR response elements (nLXREs) in their promoters [39]

1), such as EpsteinBarr virus-encoded small RNAs (EBERs) [201203], producing abortive reactivation, in which the resulting proteins can cause inflammation [204, 205] or induce the release of new virions that provoke an immune response [171]