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The interplay of NAD + /NADP + metabolism with circadian clock is further evidenced by the oscillating redox, in which ROS levels display a different liver pattern compared to other tissues due to the unique NAD + oscillation in response to the autonomous hepatic clock

Front Pharmacol 11:487

2003;8:d36991

This study was approved by the Ethics Review Committee of the Nagoya University Graduate School of Medicine (2009 0853) and conducted in accordance with all relevant guidelines

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