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The subsequent release of mucins and AMPs as well as the release of chemokines and cytokines recruits immune cells enabling pathogen concentrations to be controlled at a distance from the epithelial layer where systemic access is most likely to be achieved (Johansson et al

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Gastrointestinal disorders and surgeries Some GI-related conditions and surgeries may affect B12 absorption: Crohns disease: A chronic inflammatory disease, Crohns affects the small and large intestine particularly the distal ileum, which is where B12 is absorbed