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This leads to the release of chemotactic factors promoting leucocyte accumulation which secrete pro-oxidants and proteases mediating capillary wall injury, proteinuria, and impaired glomerular filtration rate (Sethi et al., 2019)

Ellagic acid and montelukast mitigate arsenic trioxideinduced hepatotoxicity via modulation of oxidative stress, inflammatory pathways, and mitochondrial apoptosis

These metabolic interventions aim to disrupt CSC energy production and survival mechanisms

Oxidative stress has been implicated in migraine pathophysiology, with glutathione (GSH) serving as the brains principal antioxidant