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The NOD-, LRR- and pyrin domain-containing protein (NLRP) inflammasome, a critical component of the innate immune system, is responsible for triggering caspase-1 activation and the release of proinflammatory cytokines (IL-1/IL-18), following exposure to cellular damage or infection (208)

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F.DuranA.YajimaT.PasparakisM.MoscatJ.Diaz-MecoM

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