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Currently, excessive NNMT upregulation is implicated in several scenarios, including obesity, metabolic diseases, muscle cell degeneration, and even some types of cancer [2, 4]

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doi: 10.7150/ijbs.106690 Summary Keywords AMPK, diabetic kidney disease, ferroptosis, glutathione peroxidase 4, renal tubular epithelial cells, TangShenWeiNing formula Citation Jiang Y, Chang J, Guo Y, Liu Z and Feng X (2026) TangShenWeiNing formula alleviates diabetic kidney disease by inhibiting ferroptosis via AMPK pathway in renal tubular epithelial cells

Recombinant Adenovirus Construction and Transduction The adenovirus that activates MAPK kinase 6 (MKK6(Glu)), which precisely and stably activates p38/MAPK signaling, was produced by Shanghai Gene Chem Co., Ltd

The methodology was appropriate for its claims but doesnt translate to clinical use