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Superoxide dismutase activity as a predictor of adverse outcomes in patients with nonischemic dilated cardiomyopathy

Fifteen 10weekold female wildtype C57BL/6JNarl mice were treated intranasally with 5 l of 1,800 M FITC(Ahx)CR 8 A(2535)PEI peptide, dissolved in 100 mM NaH 2 PO 4 /138 mM KCl (pH 5), for three consecutive days (9 nmole/mouse/day)

In IL-1-stimulated OA models, they upregulate SOX9 and COMP while suppressing ADAMTS4 activity, and micro-CT analysis shows 35% less subchondral bone loss