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There is a wide range of MRS sequences available to measure in vivo brain GSH, and while the current studies in AD and MCI suggests that MEGA-PRESS is a good candidate for technique standardization, recent advances in MEGA-PRESS have also allowed for simultaneous measurements of pairs of compounds such as GSH/-aminobutyric acid and N -acetyl aspartate/ N -acetyl aspartyl glutamate in one acquisition [96, 97]

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For example, conjugating of neonatal Fc-receptor-targeted peptides to PEGylated nanoparticles substantially enhances drug delivery efficiency 245

S.et al (2005)