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Compared with current therapies for RA, which show success in targeting various aspects of inflammatory pathways, the SP-based therapy in this work targeting both the synovial inflammation and RANKL-induced osteoclast differentiation is more promising as an off-the-shelf therapeutic for the alleviation of RA

(2023) 15:e44763

Once reconstituted for in-vitro use, refrigerate and use within 3045 days

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Conventional blood biomarkers like ALT and AST are released when hepatocytes die the damage has already been done, Zheng said