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Inhibiting components of the NLRP3 inflammasome, such as NLRP3 or caspase-1, has been shown to curtail hippocampal neuronal loss and deters the development of spontaneous recurrent seizures [10]

66 In the context of ARDS, abnormalities in the metabolism of amino acid can influence the development of the disease and aggravate the inflammatory response and ROS generation (Figure 3)

Colorectal cancer metastatic dMMR immuno-therapy (COMMIT) study: A randomized phase III study of atezolizumab (atezo) monotherapy versus mFOLFOX6/bevacizumab/atezo in the first-line treatment of patients (pts) with deficient DNA mismatch repair (dMMR) or microsatellite instability high (MSI-H) metastatic colorectal cancer (mCRC)NRG-GI004/SWOG-S1610

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