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While surgical denervation does not adversely affect expression of Mist1 (Fig 3B and E), muscarinic stimulation is sufficient to increase MIST1 in human cultures and suggests that although not required for acinar cell identity, acetylcholine/muscarinic signaling may act as a positive regulator of the secretory program

Left unchecked, oxidative stress accelerates aging, weakens immunity, and fuels chronic disease

2a), which can be assigned to Bi 2 S 3 -3BP (labeled with FITC)

The gene upstream of mavL is mavK (lpg2525), which appears to harbor an F-box motif known to be involved in ubiquitination 18

All patients were still alive at the time of publication of the paper, i.e., aged between 7 and 11 years [41]