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In addition, compared with a standard schedule of eating across 12-16 hours per day, limiting food intake to less than 8 hours per day was not associated with living longer

Springer Verlag, 118-141, 2002

Inflammation in the GI tract often leads to lower stomach acid which impairs the absorption of B12

No formal drug interaction studies have been conducted but interactions with other denosumab products include avoiding: calcimimetic drugs, such as cinacalcet, which may worsen hypocalcemia risk the use of other drugs associated with ONJ, such as bisphosphonates, which may increase the risk of developing ONJ

Each 10-day course should be followed by a pause of at least four months