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They result from oxidant injury to the cells, causing them to rupture

evaluated the effect of selenite-induced variation of GPx activity on the radiation resistance of three mammalian cell lines (HT29, P31, and N-18) (Table 2) [46, 47]

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Additionally, metformin can improve endometrial receptivity by increasing the expression of GLUT4 in the endometrium, regulating the expression of hormone receptors related to endometrial decidualization, and modulating autophagy and nucleic acid/protein transcription processes, which in turn improves the reproductive outcomes of PCOS

Journal of Cerebral Blood Flow & Metabolism, 33(3):339347, March 2013