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10.1186/s40035-023-00376-8 Transl

Upregulated microRNA-92b regulates the differentiation and proliferation of EpCAM-positive fetal liver cells by targeting C/EBP

Selection criteria for the eta-analysis Inclusion criteria were studies (1) including healthy participants, (2) utilising 1 H-MRS to measure GSH levels in specified brain regions, (3) giving mean and SD for each group, (4) patients with depression only and not bipolar affective disorder in accordance with criteria specified in the Diagnostic and Statistical Manual for Mental Disorders (DSM) or the International Classification of Diseases (ICD-11), (5) information provided on sex of patients

In summary, with the brain functioning on a just-in-time basis for its energy supply, the absence of reperfusion (i.e., the return to normal blood flow) or treatment allows the spread of ischemic damage from the ischemic core to the ischemic penumbra, resulting in massive brain cell death