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In summary, intervertebral disc degeneration manifests as a comprehensive deterioration of the microenvironment, including increased ECM stiffness, reduced nutrients, increased acidity, hypoxia, and exacerbated inflammatory response

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Always inject slowly and with intention for optimal patient safety, but also to protect your tools

If you have a higher body mass index or thicker subcutaneous tissue, your provider may recommend a five-eighths inch needle to ensure the medication reaches the subcutaneous fat layer beneath the skin

This location is considered safer because it is positioned away from the sciatic nerve and major blood vessels