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GHK-Cu levels in the body decline from approximately 200 ng/ml at age 20 to under 80 ng/ml by age 60 a decline of over 60%

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Notably, these studies found that simple endothelial cell cultures did not show the same angiogenic response, suggesting that BPC-157 may act as a context-dependent regulator of vascular signaling rather than a direct angiogenic stimulus

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Given the strong link between sleep function and depressive states, this peptide, which appears to influence the sleep cycle, could also be of research interest in the context of depression onset