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10.3390/ijms18122504 51 HaddadM.HerveV.Ben KhedherM

(Holyoake et al., 2016

Conversely, SAM serves as a methyl donor for the remethylation of tetrahydrofolate to form 5-methyltetrahydrofolate, closing the loop between the methionine cycle and the folate cycle

Glutathione deficiency can impair the body's ability to repair and recover from oxidative damage caused by strenuous exercise or injuries

It can also be hypothesized that the conserved function of gap junctions would facilitate proper communication between astrocytes and oligodendrocytes, promoting myelination (Papaneophytou et al., 2019)