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It is a cofactor in the metabolism of fatty acids and its derivative acetyl-L-carnitine helps regulate carbohydrate, protein, and fatty acid metabolism and cellular energy production

Acknowledgements The authors are grateful for the assistance of staff from the Experimental Animal Center and Analysis & Testing Center of Nanjing Medical University, Anhui Medical University, and Chungbuk National University

Enhanced immune response by HOTTIP-induced polarization of local and circulating macrophages to the M1 phenotype also positioned macrophage-derived lncRNAs like HOTTIP as interesting candidates for individualized cancer immunotherapy ( Recent studies indicate that the best application of macrophage-derived lncRNAs to personalized oncology is through integration of immune and molecular signatures, but not as individual markers

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Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes