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10.1016/j.joca.2013.01.014 Osteoarthr

Companies get around this by labeling it as a "research chemical not for human consumption." This means the product is completely unregulated, and you have no way of knowing if it's pure, sterile, or even contains the correct substance

Redness over an involved joint (gout is highly inflammatory) Involvement of the base of the big toe on one side (the most common site for gout) Involvement of the joints at the middle of the foot Uric acid elevation on blood testing X-ray findings of swelling of joints which is not symmetrical Joint fluid is tested for infection and is negative