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The SURMOUNT clinical trials demonstrated that tirzepatide's 4-week dose-escalation protocol led to substantial weight loss of 20% to 22% of baseline body weight over 68 weeks

It is being studied in clinical trials, including Phase 3 studies

Cardinale, RM, Benedict, SH, Kavanagh, BD, Bump, E, Mohan, R

Treating these patients is made even more challenging given the gaps of knowledge that inherently exist surrounding the safety and efficacy of many pharmacologic therapies used to treat expecting mothers

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