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These findings highlight the potential of polyphenols as GSK3 inhibitors, offering a promising therapeutic strategy to modulate tau pathology and mitigate AD progression (Figure 5ah)

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In the endothelial compartment three subpopulations characteristic of AH were found, with increased expression of pro-inflammatory, pro-angiogenic and pro-fibrotic genes as ACKR1 and PLVAP

While many of the findings cited above were observed in animal studies (and therefore cannot be extrapolated to humans), there is evidence that researchers are actively exploring BCP-157s potential in these areas

Loss of C-Kit expression in breast cancer correlates with malignant transformation of breast epithelium and is mediated by kit gene promoter DNA hypermethylation