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Figure 3 3.4 Epigenetic and signal transduction effects The regulation of epigenetics and the manipulation of signal transduction pathways have emerged as a fundamental mechanistic basis by which natural agents can exert strong anti-cancer effects in breast cancer, affecting the various stages of tumour development (initiation, progression, metastasis), and response to therapy by targeting diverse interactions between gene expression, chromatin structure, and intracellular signalling elements (198)

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The molecular responses elicited by UA in human plasma and skeletal muscle resemble those induced by conventional exercise training (7), sparking considerable interest in the sports science community

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Gallego, S