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TNF can be identified by two types of receptors that TNFR1 (51) expresses on immune and endothelial cells and TNFR2 (51) regulates cell survival and death by activating a key transcription factor named nuclear factor (NF)-B (52, 53)

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NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

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The authors included 6 RCT with 576 patients receiving various antioxidant regimens or placebo following varicocelectomy