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But if untreated, it may lead to symptoms such as: Weakness, tiredness, or lightheadedness Heart palpitations and shortness of breath Pale skin A smooth tongue Constipation, diarrhea, loss of appetite, or gas Nerve problems like numbness or tingling, muscle weakness, and problems walking Vision loss Mental problems like depression, memory loss, or behavioral changes Treatment If you have pernicious anemia or have trouble absorbing vitamin B12, you'll need shots of this vitamin at first

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doi:10.1007/s10620-015-3763-0 10Mazloom SE, Yan D, Hu JZ,

Small observational studies have reported modest weight loss, but these typically lack adequate controls for dietary modification, exercise, and placebo effects