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An increased relative abundance of Lachnospiraceae (class Clostridia ) has been observed, and reduced levels of these bacteria have been linked to inflammatory bowel disease and chronic gastrointestinal tract infections (170)

The presence of such functionally specialized zones within a single synapse is suggested by both spatiotemporal modeling of glutamate in the cleft and the flexible nanoarchitecture of active zone and PSD proteins 20,25,36,41,42,44

Outcome Measurements All primary (behavioral measurements) and secondary outcomes (intracellular glutathione levels and adverse events) were obtained at baseline and study end

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