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both the sugar and the internucleoside linkage, i.e., the backbone, of the nucleotide units are replaced with novel groups, although the base units are maintained for hybridization with an appropriate nucleic acid target compound

Alteration of transcriptional and post-transcriptional expression of -glutamylcysteine synthetase by diethyl maleate

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Molecular and Cellular Probes, 25 (2-3), 6977

Additionally, another study indicated that certain compounds found in coffee, such as chlorogenic acid, could stimulate the production of glutathione in the liver, further supporting the idea that coffee consumption may bolster our antioxidant defenses