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Ken Geraldi, Ms

10.1016/j.neuropharm.2021.108719 3 AshrafA.JeandriensJ.ParkesH

Nucleoside-5-monophosphates as prodrugs of adenosine A2A receptor agonists activated by ecto-5-nucleotidase

Figure 1 2.1 Overproduction of ROS One hallmark feature of IBD is the overproduction of ROS, which causes dysregulation of signal transduction, an inflammatory response, and DNA damage, all of which contribute to the progression and deterioration of the disease (27)