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It is found in lipoproteins like low-density lipoprotein (LDL) and very-low-density lipoprotein (VLDL), which are often associated with an increased risk of heart disease

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Notably, Org 24,598 has demonstrated the capacity to reduce cocaine self-administration in non-human primates following intravenous administration at 1.0 mg/kg across three experimental sessions, as well as in rodent models at intraperitoneal doses ranging from 3.0 to 7.5 mg/kg, supporting its role in attenuating cocaine-seeking behavior (Achat-Mendes et al