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Committee on toxicity of chemicals in food consumer products and the environment

Linus Pauling Institute Oregon State University Updated in September 2016 by: Barbara Delage, Ph.D

This induction accelerates the clearance of drugs that rely on UGT-mediated metabolism (e.g., capecitabine), potentially resulting in insufficient therapeutic exposure to the chemotherapeutic agent and thereby impairing its antitumor efficacy